Invention Grant
- Patent Title: Purification of sulfobutylated cyclodextrins with specific ion exchange resins
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Application No.: US17344217Application Date: 2021-06-10
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Publication No.: US11649299B2Publication Date: 2023-05-16
- Inventor: Tamas Sohajda , Gabriella Hirschbergne Szejtli , István Puskás
- Applicant: CYCLOLAB CYCLODEXTRIN RESEARCH AND DEVELOPMENT LABORATORY LTD.
- Applicant Address: HU Budapest
- Assignee: CYCLOLAB CYCLODEXTRIN RESEARCH AND DEVELOPMENT LABORATORY LTD.
- Current Assignee: CYCLOLAB CYCLODEXTRIN RESEARCH AND DEVELOPMENT LABORATORY LTD.
- Current Assignee Address: HU Budapest
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Main IPC: C08B37/16
- IPC: C08B37/16 ; C08B37/00 ; B01J39/05 ; B01J41/05

Abstract:
Present invention relates to a process to reduce butane sultone hydrolysis products (4-hydroxybutane-1-sulfonic acid, and bis(4-sulfobutyl) ether disodium) in sulfobutylether cyclodextrin reaction mixtures achieved with the combined use of a strong anion exchange resin having dialkyl 2-hydroxyethyl ammonium hydroxide functionality and a cation exchange resin.
Public/Granted literature
- US20220396641A1 PURIFICATION OF SULFOBUTYLATED CYCLODEXTRINS WITH SPECIFIC ION EXCHANGE RESINS Public/Granted day:2022-12-15
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