Low-noise optical differential receivers are described. Such differential receivers may include a differential amplifier having first and second inputs and first and second outputs, and four photodetectors. A first and a second of such photodetectors are coupled to the first input of the differential amplifier, and a third and a fourth of such photodetectors are coupled to the second input of the differential amplifier. The anode of the first photodetector and the cathode of the second photodetector are coupled to the first input of the differential amplifier. The cathode of the third photodetector and the anode of the fourth photodetector are coupled to the second input of the differential amplifier. The optical receiver may involve two stages of signal subtraction, which may significantly increase noise immunity.