Invention Grant
- Patent Title: Methods for purifying antibodies having reduced high molecular weight aggregates
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Application No.: US16640755Application Date: 2018-08-22
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Publication No.: US11697670B2Publication Date: 2023-07-11
- Inventor: Matthew Westoby , Greg Evangelist
- Applicant: Biogen MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2018/047609 2018.08.22
- International Announcement: WO2019/040671A 2019.02.28
- Date entered country: 2020-02-21
- Main IPC: C07K1/14
- IPC: C07K1/14 ; C07K1/36 ; C07K16/00 ; C07K1/18 ; C07K1/20 ; C07K1/22 ; C07K16/06 ; A61K39/395
Abstract:
Provided herein, in some embodiments, are methods and compositions for purifying antibodies from cellular cultures using one or more thiol containing additives during a purification process, for example in a chromatographic purification process.
Public/Granted literature
- US20210130397A1 METHODS FOR PURIFYING ANTIBODIES HAVING REDUCED HIGH MOLECULAR WEIGHT AGGREGATES Public/Granted day:2021-05-06
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