Invention Grant
- Patent Title: Nucleolin-targeting aptamers and methods of using the same
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Application No.: US16645762Application Date: 2018-09-10
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Publication No.: US11713464B2Publication Date: 2023-08-01
- Inventor: Bruce A. Sullenger , Michael Goldstein , Elizabeth D. Pratico , Michael Kastan , Bethany Gray
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Quarles & Brady LLP
- International Application: PCT/US2018/050240 2018.09.10
- International Announcement: WO2019/051397A 2019.03.14
- Date entered country: 2020-03-09
- Main IPC: C12N15/115
- IPC: C12N15/115 ; A61P35/00 ; C12Q1/68
Abstract:
Provided herein are compositions including aptamers capable of binding to and/or inhibiting the activity of nucleolin. Methods of treating cancer in a subject by administering such compositions are also provided.
Public/Granted literature
- US20200283773A1 NUCLEOLIN-TARGETING APTAMERS AND METHODS OF USING THE SAME Public/Granted day:2020-09-10
Information query
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