Invention Grant
- Patent Title: Compositions and methods for inducing scarring by peri-tumoral cells
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Application No.: US16696960Application Date: 2019-11-26
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Publication No.: US11998614B2Publication Date: 2024-06-04
- Inventor: Tarun Saxena , Ravi Bellamkonda , Nassir Mokarram-Dorri
- Applicant: Duke University
- Applicant Address: US NC Durham
- Assignee: DUKE UNIVERSITY
- Current Assignee: DUKE UNIVERSITY
- Current Assignee Address: US NC Durham
- Agency: Talem IP Law, LLP
- Main IPC: A61K47/69
- IPC: A61K47/69 ; A61K47/65 ; B82Y5/00 ; C07K14/705
Abstract:
Compositions are provided, the compositions comprising: (1) a nanoparticle; (2) optionally, a linker and/or masking agent; and (3) a ligand configured to activate peri-tumoral cells to induce scarring by the peri-tumoral cells. In some aspects, administration of the compositions to a subject may generate an environment capable of walling-off and containing invasive tumors.
Public/Granted literature
- US20200171168A1 COMPOSITIONS AND METHODS FOR INDUCING SCARRING BY PERI-TUMORAL CELLS Public/Granted day:2020-06-04
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