Invention Grant
- Patent Title: Use of cation-exchange chromatography in the flow-through mode to enrich post-translational modifications
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Application No.: US17718116Application Date: 2022-04-11
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Publication No.: US12018046B2Publication Date: 2024-06-25
- Inventor: Austen Ng , Robert S. Gronke
- Applicant: Biogen MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen MA Inc.
- Current Assignee: Biogen MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07K1/18
- IPC: C07K1/18 ; C07K14/715 ; C07K14/755

Abstract:
The present invention relates to improved methods in the separation recombinant polypeptides with post-translational modifications from complex mixtures through the use of a cation exchange medium.
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