Invention Grant
- Patent Title: Engineered retrons and methods of use
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Application No.: US18472824Application Date: 2023-09-22
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Publication No.: US12054739B2Publication Date: 2024-08-06
- Inventor: Alim Ladha , Vladimir Presnyak , Inna Shcherbakova , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
- Applicant: ReNAgade Therapeutics Management Inc.
- Applicant Address: US MA Cambridge
- Assignee: RENAGADE THERAPEUTICS MANAGEMENT INC.
- Current Assignee: RENAGADE THERAPEUTICS MANAGEMENT INC.
- Current Assignee Address: US MA Cambridge
- Agency: Duane Morris LLP
- Agent Thomas J. Kowalski; Lawrence P. Casson
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12N9/12 ; C12N15/11 ; C12N15/90

Abstract:
Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
Public/Granted literature
- US20240175058A1 ENGINEERED RETRONS AND METHODS OF USE Public/Granted day:2024-05-30
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