Invention Publication
- Patent Title: ENGINEERED RETRONS AND METHODS OF USE
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Application No.: US18472824Application Date: 2023-09-22
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Publication No.: US20240175058A1Publication Date: 2024-05-30
- Inventor: Alim Ladha , Vladimir Presnyak , Inna Shcherbakova , Brian Goodman , Mario Rodriguez Mestre , Devin Scott Quinlan , Muthusamy Jayaraman , Stephen Scully
- Applicant: ReNAgade Therapeutics Management Inc.
- Applicant Address: US MA Cambridge
- Assignee: ReNAgade Therapeutics Management Inc.
- Current Assignee: ReNAgade Therapeutics Management Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C12N15/90
- IPC: C12N15/90 ; C12N9/12 ; C12N9/22 ; C12N15/11
Abstract:
Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
Public/Granted literature
- US12054739B2 Engineered retrons and methods of use Public/Granted day:2024-08-06
Information query
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