Invention Grant
- Patent Title: Prefusion-stabilized hMPV F proteins
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Application No.: US18411284Application Date: 2024-01-12
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Publication No.: US12077563B2Publication Date: 2024-09-03
- Inventor: Jason McLellan , Ching-Lin Hsieh , Scott Rush , Nianshuang Wang
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: C07K14/08
- IPC: C07K14/08 ; C07K14/115 ; C07K14/135
Abstract:
Provided herein are engineered hMPV F proteins. In some aspects, the engineered F proteins exhibit enhanced conformational stability and/or antigenicity. Methods are also provided for use of the engineered F proteins as diagnostics, in screening platforms, and/or in vaccine compositions.
Public/Granted literature
- US20240140994A1 PREFUSION-STABILIZED HMPV F PROTEINS Public/Granted day:2024-05-02
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