Invention Publication
- Patent Title: PREFUSION-STABILIZED HMPV F PROTEINS
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Application No.: US18411284Application Date: 2024-01-12
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Publication No.: US20240140994A1Publication Date: 2024-05-02
- Inventor: Jason MCLELLAN , Ching-Lin HSIEH , Scott RUSH , Nianshuang WANG
- Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Main IPC: C07K14/08
- IPC: C07K14/08
Abstract:
Provided herein are engineered hMPV F proteins. In some aspects, the engineered F proteins exhibit enhanced conformational stability and/or antigenicity. Methods are also provided for use of the engineered F proteins as diagnostics, in screening platforms, and/or in vaccine compositions.
Public/Granted literature
- US12077563B2 Prefusion-stabilized hMPV F proteins Public/Granted day:2024-09-03
Information query
