- Patent Title: Functional and therapeutic effects of PAR4 cleavage by cathepsin G
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Application No.: US17934816Application Date: 2022-09-23
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Publication No.: US12077607B2Publication Date: 2024-09-03
- Inventor: Paul F. Bray , Robert A. Campbell , Michelle Stoller
- Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Applicant Address: US UT Salt Lake City
- Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee Address: US UT Salt Lake City
- Agency: Michael Best & Friedrich LLP
- Main IPC: C07K7/06
- IPC: C07K7/06 ; A61P7/04 ; A61K38/00

Abstract:
Disclosed herein are a synthetic peptide mimetic and compositions comprising the synthetic peptide mimetic that induce activation of and signaling through PAR4. Also disclosed herein are methods of treating a bleeding disorder comprising administering the synthetic peptide.
Public/Granted literature
- US20230126796A1 FUNCTIONAL AND THERAPEUTIC EFFECTS OF PAR4 CLEAVAGE BY CATHEPSIN G Public/Granted day:2023-04-27
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