The present disclosure provides a core-sheath filament. The core-sheath filament includes an adhesive core and a non-tacky sheath, wherein the sheath exhibits a melt flow index of less than 15 grams per 10 minutes. The present disclosure also provides a method of printing an adhesive. The method includes a) melting a core-sheath filament in a nozzle to form a molten composition, and b) dispensing the molten composition through the nozzle onto a substrate. Steps a) and b) are carried out one or more times to form a printed adhesive. The core-sheath filament includes an adhesive core and a non-tacky sheath. Further, methods are provided, including receiving, by a manufacturing device having one or more processors, a digital object comprising data specifying an article; and generating, with the manufacturing device by an additive manufacturing process using a core-sheath filament, the article including a printed adhesive based on the digital object. A system is also provided, including a display that displays a 3D model of an article; and one or more processors that, in response to the 3D model selected by a user, cause a 3D printer to create a physical object of an article including a printed adhesive, using a core-sheath filament.