The invention relates to a sealed container (1) comprising a container body (2) having a through-hole (8) that is delimited by a flange and is closed by a removable door (7) mounted on the flange and an annular seal located between the flange and the door (7), characterized in that the flange consists of two separate concentric sleeves, one of the sleeves defining an outer flange body (5) arranged to allow a connection of the container body (2) to a flange having a complementary shape on an enclosure, the other sleeve defining an inner flange body (6) arranged to allow a connection of the door (7) to the flange, the outer flange body (5) being made entirely or partially of a resistant plastic material selected from plastics that are resistant to autoclave sterilization cycles, while the inner flange body (6) is made of a metal alloy.