An airbrush cleaning system is disclosed which includes a nose cap configured to sealingly fit on a spray nose assembly of an airbrush, a reservoir cap configured to sealingly fit over a liquid reservoir of the airbrush, a first tether connecting the bulb nose cap and the reservoir cap, a cap plug configured to seal off an air inlet port of the airbrush, a lever block configured to hold an airbrush needle valve in the open position, and a second tether connecting the cap plug and the lever block. A kit including the cleaning system and the airbrush and a method for using the cleaning system are also disclosed.