Invention Publication
![SALT AND CRYSTAL FORMS OF 4-AMINO-5-(6-(4-METHYLPIPERAZIN-1-YL)-1H-BENZO[D]IMIDAZOL-2-YL)THIENO[2,3-B]PYRIDIN-6(7H)-ONE](/docs/US/2023-06-08/US20230174549A1/abs.jpg.600x600.jpg)
- Patent Title: SALT AND CRYSTAL FORMS OF 4-AMINO-5-(6-(4-METHYLPIPERAZIN-1-YL)-1H-BENZO[D]IMIDAZOL-2-YL)THIENO[2,3-B]PYRIDIN-6(7H)-ONE
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Application No.: US17924220Application Date: 2021-05-10
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Publication No.: US20230174549A1Publication Date: 2023-06-08
- Inventor: Mark R. Bray , Sze-Wan Li
- Applicant: UNIVERSITY HEALTH NETWORK
- Applicant Address: CA Toronto
- Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee: UNIVERSITY HEALTH NETWORK
- Current Assignee Address: CA Toronto
- International Application: PCT/CA2021/050645 2021.05.10
- Date entered country: 2022-11-09
- Main IPC: C07D495/04
- IPC: C07D495/04 ; C07C59/255 ; A61K45/06
![SALT AND CRYSTAL FORMS OF 4-AMINO-5-(6-(4-METHYLPIPERAZIN-1-YL)-1H-BENZO[D]IMIDAZOL-2-YL)THIENO[2,3-B]PYRIDIN-6(7H)-ONE](/abs-image/US/2023/06/08/US20230174549A1/abs.jpg.150x150.jpg)
Abstract:
A novel salt form of Compound (I) represented by the following structural formula, and its corresponding pharmaceutical compositions, are disclosed. (I), Particular single crystalline forms of 1:1 Compound (I) tartrate salt are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms are also disclosed. The present disclosure also provides methods of treating cancer in a subject.
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