Invention Publication
- Patent Title: CHIMERIC ANTIGEN RECEPTOR-MODIFIED GRANULOCYTE-MACROPHAGE PROGENITORS FOR CANCER IMMUNOTHERAPY
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Application No.: US18561889Application Date: 2022-05-19
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Publication No.: US20240240147A1Publication Date: 2024-07-18
- Inventor: Qi-Long Ying , Shi Yue , Xueyuan Jing
- Applicant: University of Southern California
- Applicant Address: US CA Los Angeles
- Assignee: University of Southern California
- Current Assignee: University of Southern California
- Current Assignee Address: US CA Los Angeles
- International Application: PCT/US2022/030109 2022.05.19
- Date entered country: 2023-11-17
- Main IPC: C12N5/0787
- IPC: C12N5/0787 ; A61K39/00 ; A61P35/02 ; C07K14/705 ; C12N5/0786 ; C12N5/0789 ; C12N15/86
Abstract:
The disclosure provides methods to genetically engineer granulocyte-macrophage progenitors (GMPs) to express a chimeric antigen receptor (CAR), and uses thereof, including for cancer immunotherapy.
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