Invention Grant
- Patent Title: Histone deacetylase inhibitors
- Patent Title (中): 组蛋白脱乙酰酶抑制剂
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Application No.: US10803575Application Date: 2004-03-17
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Publication No.: US07381825B2Publication Date: 2008-06-03
- Inventor: Jerome C. Bressi , Jason W. Brown , Sheldon X. Cao , Anthony R. Gangloff , Andrew J. Jennings , Jeffrey A. Stafford , Phong H. Vu , Xiao-Yi Xiao
- Applicant: Jerome C. Bressi , Jason W. Brown , Sheldon X. Cao , Anthony R. Gangloff , Andrew J. Jennings , Jeffrey A. Stafford , Phong H. Vu , Xiao-Yi Xiao
- Applicant Address: US CA San Diego
- Assignee: Takeda San Diego, Inc.
- Current Assignee: Takeda San Diego, Inc.
- Current Assignee Address: US CA San Diego
- Agent C. Amy Smith
- Main IPC: C07D401/04
- IPC: C07D401/04
Abstract:
Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
Public/Granted literature
- US20040254220A1 Histone deacetylase inhibitors Public/Granted day:2004-12-16
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