Invention Grant
- Patent Title: Depth selective pH measurement and UV exposure measurement
- Patent Title (中): 深度选择性pH测量和紫外线曝光测量
-
Application No.: US10506056Application Date: 2002-02-28
-
Publication No.: US07656522B2Publication Date: 2010-02-02
- Inventor: Gerwin Jan Puppels , Peter Jacobus Caspers , Gerhardus Wilhelmus Lucassen
- Applicant: Gerwin Jan Puppels , Peter Jacobus Caspers , Gerhardus Wilhelmus Lucassen
- Applicant Address: NL Rotterdam
- Assignee: River Diagnostics B.V.
- Current Assignee: River Diagnostics B.V.
- Current Assignee Address: NL Rotterdam
- Agency: Hoffman & Baron, LLP
- International Application: PCT/NL02/00132 WO 20020228
- International Announcement: WO03/073082 WO 20030904
- Main IPC: G01J3/44
- IPC: G01J3/44

Abstract:
A Raman spectrum is measured inside animal tissue, such us human skin tissue, at a selected depth from a surface the tissue. A pH value is computed using a function that assigns a pH value as a function of the measured Raman spectrum. The computation may involve computing a number representing a ratio of concentrations of a protonated and a deprotonated version of a chemical substance from the Raman spectrum and generating pH information on the basis of said number. The chemical substance is for example a form of Urocanic acid (UCA). UV exposure is measured from the weight of the spectrum of cis-UCA.
Public/Granted literature
- US20050117150A1 Depth selective ph measurement and uv exposure measurement Public/Granted day:2005-06-02
Information query