Invention Grant
- Patent Title: Hydroisoindoline tachykinin receptor antagonists
- Patent Title (中): 羟基异吲哚啉速激肽受体拮抗剂
-
Application No.: US11920286Application Date: 2006-06-23
-
Publication No.: US07683068B2Publication Date: 2010-03-23
- Inventor: Jinlong Jiang , Robert J. DeVita , Sanjeev Kumar , Sander G. Mills , Richard A. Tschirret-Guth
- Applicant: Jinlong Jiang , Robert J. DeVita , Sanjeev Kumar , Sander G. Mills , Richard A. Tschirret-Guth
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Yong Zhao; Valerie J. Camara
- International Application: PCT/US2006/024568 WO 20060623
- International Announcement: WO2007/002457 WO 20070104
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K31/4035 ; A61K31/4439 ; C07D209/46 ; C07D405/04 ; C07D409/04 ; A61P29/00
Abstract:
The present invention is directed to certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
Public/Granted literature
- US20090054462A1 Hydroisoindoline tachykinin receptor antagonists Public/Granted day:2009-02-26
Information query
IPC分类:
