Invention Grant
US07696162B2 Zinc-free and low-zinc insulin preparations having improved stability
有权
具有改善的稳定性的无锌和低锌胰岛素制剂
- Patent Title: Zinc-free and low-zinc insulin preparations having improved stability
- Patent Title (中): 具有改善的稳定性的无锌和低锌胰岛素制剂
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Application No.: US12285464Application Date: 2008-10-06
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Publication No.: US07696162B2Publication Date: 2010-04-13
- Inventor: Peter Boderke
- Applicant: Peter Boderke
- Applicant Address: DE Frankfurt am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: DE10114178 20010323
- Main IPC: A61K38/28
- IPC: A61K38/28
Abstract:
The invention relates to a formulation comprising a polypeptide selected from at least one of insulin, an insulin metabolite, an insulin analog, and an insulin derivative; at least one surfactant; optionally at least one preservative; and optionally at least one of an isotonicizing agent, a buffer or an excipient, wherein the formulation is free from or low in zinc. The invention also relates to the production of such insulin preparations and their use as pharmaceutical formulations.
Public/Granted literature
- US20090186807A1 Zinc-free and low-zinc insulin preparations having improved stability Public/Granted day:2009-07-23
Information query
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