Invention Grant
US07858928B2 Nanostructured surfaces as a dual ionization LDI-DESI platform for increased peptide coverage in proteomic analysis
失效
纳米结构表面作为双电离LDI-DESI平台，用于在蛋白质组学分析中增加肽覆盖
- Patent Title: Nanostructured surfaces as a dual ionization LDI-DESI platform for increased peptide coverage in proteomic analysis
- Patent Title (中): 纳米结构表面作为双电离LDI-DESI平台，用于在蛋白质组学分析中增加肽覆盖
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Application No.: US11858859Application Date: 2007-09-20
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Publication No.: US07858928B2Publication Date: 2010-12-28
- Inventor: Daniel R. Knapp
- Applicant: Daniel R. Knapp
- Applicant Address: US DC Washington
- Assignee: The United States of America Department of Health and Human Services
- Current Assignee: The United States of America Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Pabst Patent Group
- Main IPC: H01J49/04
- IPC: H01J49/04
Abstract:
Embodiments of the invention include methods and devices for the analysis of proteins utilizing a gold coated nanoporous alumina surface for dual ionization mode mass spectrometric analysis using desorption electrospray ionization (DESI) and laser desorption ionization (LDI). Combined use of DESI and LDI gives increased sequence coverage in peptide mixture analysis from a single sample preparation.
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