Methods and related apparatuses for chemically analyzing at least one sample of fluid, such that a gas flow of at least one fluid sample is directed into a mixing region of an ion mobility device, wherein the mixing region is in communication with at least one container having at least one other fluid. Further, creating an ion flow of gaseous ions, a mixture of gaseous ions or a gaseous neutral species from the at least one sample and the at least one other fluid. Further still, injecting the ion flow from the mixing region into at least one ion mobility assembly of the ion mobility device, the at least one ion mobility assembly comprising at least one mobility tube; and, detecting the ions from the ion flow exiting the ion mobility assembly.