Test equipment determines the contents of medical fluids to be delivered to a patient by a medication delivery system by measuring optical properties of the fluids. One system provides a non-invasive test that uses optical rotation caused by optically active pharmaceutical substances to determine the presence or absence of the pharmaceutical substances within a medical fluid. Another system provides a non-invasive test that uses refractive index properties to determine the concentration of a pharmaceutical substance within the fluid. A method for use is also disclosed.