Invention Grant
US08133995B2 Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
有权
用于治疗高增殖性疾病和与血管发生相关的疾病的取代的4-氨基吡咯并三嗪衍生物
- Patent Title: Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
- Patent Title (中): 用于治疗高增殖性疾病和与血管发生相关的疾病的取代的4-氨基吡咯并三嗪衍生物
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Application No.: US12085879Application Date: 2006-11-30
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Publication No.: US08133995B2Publication Date: 2012-03-13
- Inventor: Julie Dixon , Steven Magnuson , Barton Phillips , Yamin Wang , Tandy Li , Kyle Parcella , Jason Newcom , Harold Kluender , Zhenqiu Hong , Brent Chandler , Zhonghua Zhang , Kristen Allegue , Zheng Liu
- Applicant: Julie Dixon , Steven Magnuson , Barton Phillips , Yamin Wang , Tandy Li , Kyle Parcella , Jason Newcom , Harold Kluender , Zhenqiu Hong , Brent Chandler , Zhonghua Zhang , Kristen Allegue , Zheng Liu
- Applicant Address: US NY Tarrytown
- Assignee: Bayer HealthCare LLC
- Current Assignee: Bayer HealthCare LLC
- Current Assignee Address: US NY Tarrytown
- Agency: Edwards Wildman Palmer LLP
- Agent Barry Kramer; Nicholas J. DiCeglie, Jr.
- International Application: PCT/US2006/045996 WO 20061130
- International Announcement: WO2007/064883 WO 20070607
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D417/02 ; C07D413/02 ; A61K31/53 ; A61P35/00

Abstract:
This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
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