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1.发明申请SUBSTITUTED 4-AMINO-PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS 有权取代的4-氨基吡咯烷酮衍生物有助于治疗与增殖性疾病有关的高血压病和疾病公开(公告)号：US20120165314A1
公开(公告)日：2012-06-28
申请号：US13414392
申请日：2012-03-07
Applicant: Julie Dixon , Barton Phillips , Yamin Wang , Tindy Li , Kyle Parcella , Jason Newcom , Harold C.E. Kluender , Zhenqiu Hong , Brent Chandler , Zhonghua Zhang , Steven Magnuson , Kristen M. Allegue , Zheng Liu
Inventor： Julie Dixon , Barton Phillips , Yamin Wang , Tindy Li , Kyle Parcella , Jason Newcom , Harold C.E. Kluender , Zhenqiu Hong , Brent Chandler , Zhonghua Zhang , Steven Magnuson , Kristen M. Allegue , Zheng Liu
IPC: A61K31/53 , A61P35/00 , A61K31/541 , A61K31/553 , C07D487/04 , A61K31/5377
CPC classification number: C07D487/04
Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
Abstract translation: 本发明涉及新颖的吡唑并三嗪化合物，含有这些化合物的药物组合物以及这些化合物和组合物用于预防和/或治疗与血管发生相关的高增殖性障碍和疾病的用途。
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2.发明申请PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING CANCER THROUGH INHIBITION OF AURORA KINASE 有权用于通过抑制激素激酶治疗癌症的吡咯烷酮衍生物公开(公告)号：US20100273800A1
公开(公告)日：2010-10-28
申请号：US12679787
申请日：2008-09-22
Applicant: Steven Magnuson , Philip Wickens , Zhonghua Zhang , Ning Qi , Xin Ma
Inventor： Steven Magnuson , Philip Wickens , Zhonghua Zhang , Ning Qi , Xin Ma
IPC: A61K31/53 , C07D253/10 , C12N9/99 , A61P35/00 , A61J1/05
CPC classification number: C07D487/04
Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly Cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly Cancer.
Abstract translation: 本发明涉及新化合物及其制备方法，治疗疾病，特别是癌症的方法，包括给药所述化合物，以及制备用于治疗或预防病症，特别是癌症的药物组合物的方法。
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3.发明申请PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS 有权用于治疗与促血细胞生成相关的高血压疾病和疾病的吡咯烷酮衍生物公开(公告)号：US20100075958A1
公开(公告)日：2010-03-25
申请号：US12506033
申请日：2009-07-20
Applicant: Julie A. Dixon , Catherine Brennan , Karl Miranda , Brent Chandler , Barton Phillips , Jianmei Fan , Michael Brands , Andrea McClure , Benjamin Jones , Wenlang Fu , Donald Bierer , Steven Magnuson , Harold C.E. Kluender
Inventor： Julie A. Dixon , Catherine Brennan , Karl Miranda , Brent Chandler , Barton Phillips , Jianmei Fan , Michael Brands , Andrea McClure , Benjamin Jones , Wenlang Fu , Donald Bierer , Steven Magnuson , Harold C.E. Kluender
IPC: A61K31/53 , C07D471/04 , A61K31/5377 , A61P35/00
CPC classification number: C07D491/113 , C07D487/04
Abstract: This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
Abstract translation: 本发明涉及吡咯并三嗪化合物，含有这些化合物的药物组合物以及这些化合物和组合物用于预防和/或治疗与血管发生相关的高增殖性病症和疾病的用途。
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公开(公告)号：US20080064734A1
公开(公告)日：2008-03-13
申请号：US11897620
申请日：2007-08-31
Applicant: Joachim Rudolph , Louis-David Cantin , Steven Magnuson , William Bullock , Ann-Marie Bullion , Libing Chen , Chih-Yuan Chuang , Sidney Liang , Dyuti Majumdar , Herbert Ogutu , Alan Olague , Ning Qi , Philip Wickens
Inventor： Joachim Rudolph , Louis-David Cantin , Steven Magnuson , William Bullock , Ann-Marie Bullion , Libing Chen , Chih-Yuan Chuang , Sidney Liang , Dyuti Majumdar , Herbert Ogutu , Alan Olague , Ning Qi , Philip Wickens
IPC: A61K31/415 , A61P3/04 , C07D231/10
CPC classification number: C07D231/38 , C07D401/04 , C07D403/12 , C07D413/12 , C07D471/04
Abstract: The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
Abstract translation: 本发明涉及苯胺基吡唑化合物，药物组合物和治疗糖尿病及相关疾病的方法。
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5.发明申请2,6-Substituted chroman derivatives useful as beta-3 adrenoreceptor agonists 审中-公开用作β-3肾上腺素受体激动剂的2,6-取代的苯并二氢吡喃衍生物公开(公告)号：US20050215594A1
公开(公告)日：2005-09-29
申请号：US11117759
申请日：2005-04-28
Applicant: Stephen O'Connor , Gaetan Ladouceur , William Bullock , Ann-Marie Campbell , Miao Dai , Robert Dally , Jacques Dumas , Holia Hatoum-Mokdad , Uday Khire , Wendy Lee , Qingjie Liu , Derek Lowe , Steven Magnuson , Ning Qi , Tatiana Skelekhin , Quanrong Shen , Roger Smith , Ming Wang
Inventor： Stephen O'Connor , Gaetan Ladouceur , William Bullock , Ann-Marie Campbell , Miao Dai , Robert Dally , Jacques Dumas , Holia Hatoum-Mokdad , Uday Khire , Wendy Lee , Qingjie Liu , Derek Lowe , Steven Magnuson , Ning Qi , Tatiana Skelekhin , Quanrong Shen , Roger Smith , Ming Wang
IPC: A61K31/353 , A61K31/357 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/506 , A61K31/69 , A61P1/04 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/48 , A61P9/10 , A61P13/12 , C07D311/58 , C07D405/12 , C07D405/14 , C07D407/04 , C07D407/12 , C07D407/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/14 , C07D45/02
CPC classification number: C07D405/12 , C07D311/58 , C07D405/14 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/14
Abstract: This invention relates to novel 2,6-substituted chroman derivatives which are useful in the treatment of beta-3 adrenoreceptor-mediated conditions.
Abstract translation: 本发明涉及可用于治疗β-3肾上腺素受体介导的病症的新的2,6-取代的苯并二氢吡喃衍生物。
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Patent Agency Ranking
6.发明授权Substituted 4-amino-pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis 有权用于治疗高增殖性疾病和与血管发生相关的疾病的取代的4-氨基吡咯并三嗪衍生物公开(公告)号：US08133995B2
公开(公告)日：2012-03-13
申请号：US12085879
申请日：2006-11-30
Applicant: Julie Dixon , Steven Magnuson , Barton Phillips , Yamin Wang , Tandy Li , Kyle Parcella , Jason Newcom , Harold Kluender , Zhenqiu Hong , Brent Chandler , Zhonghua Zhang , Kristen Allegue , Zheng Liu
Inventor： Julie Dixon , Steven Magnuson , Barton Phillips , Yamin Wang , Tandy Li , Kyle Parcella , Jason Newcom , Harold Kluender , Zhenqiu Hong , Brent Chandler , Zhonghua Zhang , Kristen Allegue , Zheng Liu
IPC: C07D487/04 , C07D417/02 , C07D413/02 , A61K31/53 , A61P35/00
CPC classification number: C07D487/04
Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
Abstract translation: 本发明涉及新颖的吡唑并三嗪化合物，含有这些化合物的药物组合物以及这些化合物和组合物用于预防和/或治疗与血管发生相关的高增殖性障碍和疾病的用途。
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7.发明申请PYRROLOTRIAZINE DERIVATIVES USEFUL FOR TREATING CANCER THROUGH INHIBITION OF AURORA KINASE 有权用于通过抑制激素激酶治疗癌症的吡咯烷酮衍生物公开(公告)号：US20110021518A1
公开(公告)日：2011-01-27
申请号：US12085850
申请日：2006-12-01
Applicant: Steven Magnuson , Julie Dixon , Barton Phillips , Uday Khire , Lei Wang , Zhonghua Zhang , Manoj Patel , Ellalahewage Sathyajith Kumarasinghe , Philip Wickens , Alan Olague
Inventor： Steven Magnuson , Julie Dixon , Barton Phillips , Uday Khire , Lei Wang , Zhonghua Zhang , Manoj Patel , Ellalahewage Sathyajith Kumarasinghe , Philip Wickens , Alan Olague
IPC: A61K31/5377 , C07D487/04 , A61K31/53 , C07D413/14 , A61P35/00
CPC classification number: C07D487/04 , C07D519/00
Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly Cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly Cancer.
Abstract translation: 本发明涉及新化合物及其制备方法，治疗疾病，特别是癌症的方法，包括给药所述化合物，以及制备用于治疗或预防病症，特别是癌症的药物组合物的方法。
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8.发明申请Substituted 4-Amino-Pyrrolotriazine Derivatives Useful for Treating Hyper-Proliferative Disorders and Diseases Associated with Angiogenesis 有权用于治疗与血管发生相关的超增殖性疾病和疾病的取代的4-氨基 - 吡咯并嗪衍生物公开(公告)号：US20100063038A1
公开(公告)日：2010-03-11
申请号：US12085880
申请日：2006-12-01
Applicant: Julie Dixon , Barton Phillips , Furahi Achebe , Harold Kluender , Jason Newcom , Kyle Parcella , Stephen J. O'Connor , Steven Magnuson , Zhenqui Hong , Zhonghua Zhang , Zheng Liu , Uday Khire , Lei Wang , Martin Michels , Brent Chandler
Inventor： Julie Dixon , Barton Phillips , Furahi Achebe , Harold Kluender , Jason Newcom , Kyle Parcella , Stephen J. O'Connor , Steven Magnuson , Zhenqui Hong , Zhonghua Zhang , Zheng Liu , Uday Khire , Lei Wang , Martin Michels , Brent Chandler
IPC: A61K31/53 , C07D487/04 , A61K31/5377 , A61K31/541 , C12N5/00 , A61P35/00
CPC classification number: C07D487/04
Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and and the use of those compounds or compositions for treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
Abstract translation: 本发明涉及新颖的吡咯并三嗪化合物，含有这些化合物的药物组合物，以及用作治疗高增殖和/或血管生成障碍的那些化合物或组合物作为唯一试剂或与其它活性成分组合的用途。
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9.发明申请公开(公告)号：US20090209451A1
公开(公告)日：2009-08-20
申请号：US12422804
申请日：2009-04-13
Applicant: Joachim Rudolph , Phillip Wickens , Chih-Yuan Chuang , Libing Chen , Steven Magnuson , Alan Olague , Ning Qi
Inventor： Joachim Rudolph , Phillip Wickens , Chih-Yuan Chuang , Libing Chen , Steven Magnuson , Alan Olague , Ning Qi
IPC: A61K38/02 , C07D401/12 , A61K31/4439 , A61K31/506 , C07D403/12 , C07D413/14 , A61K31/5377 , A61P3/10
CPC classification number: C07D401/12 , C07D403/12 , C07D405/12 , C07D409/14
Abstract: The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.
Abstract translation: 本发明涉及杂芳基氨基吡唑化合物，药物组合物和治疗糖尿病和相关疾病的方法。
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10.发明授权Pyrrolotriazine derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis 有权可用于治疗高增殖性疾病和与血管发生相关的疾病的吡咯嗪衍生物公开(公告)号：US07563791B2
公开(公告)日：2009-07-21
申请号：US11596913
申请日：2005-06-03
Applicant: Julie A. Dixon , Catherine Brennan , Karl Miranda , Brent Chandler , Barton Phillips , Jianmei Fan , Michael Brands , Andrea McClure , Benjamin Jones , Wenlang Fu , Donald Bierer , Steven Magnuson , Harold C. E. Kluender
Inventor： Julie A. Dixon , Catherine Brennan , Karl Miranda , Brent Chandler , Barton Phillips , Jianmei Fan , Michael Brands , Andrea McClure , Benjamin Jones , Wenlang Fu , Donald Bierer , Steven Magnuson , Harold C. E. Kluender
IPC: C07D487/04 , C07D417/02 , C07D413/02 , A61K31/53 , A61K35/00
CPC classification number: C07D491/113 , C07D487/04
Abstract: This invention relates to novel pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.
Abstract translation: 本发明涉及新颖的吡唑并三嗪化合物，含有这些化合物的药物组合物以及这些化合物和组合物用于预防和/或治疗与血管发生相关的高增殖性障碍和疾病的用途。
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