Invention Grant
- Patent Title: Excitatory glycine receptors and methods
- Patent Title (中): 兴奋性甘氨酸受体和方法
-
Application No.: US12842974Application Date: 2010-07-23
-
Publication No.: US08193315B2Publication Date: 2012-06-05
- Inventor: Stuart A. Lipton , Dongxian Zhang , Jon E. Chatterton , Kevin A. Sevarino , Marc Awobuluyi
- Applicant: Stuart A. Lipton , Dongxian Zhang , Jon E. Chatterton , Kevin A. Sevarino , Marc Awobuluyi
- Applicant Address: US CA La Jolla US CT New Haven US MA Boston
- Assignee: Sanford-Burnham Medical Research Institute,Yale University,The Brigham and Women's Hospital, Inc.
- Current Assignee: Sanford-Burnham Medical Research Institute,Yale University,The Brigham and Women's Hospital, Inc.
- Current Assignee Address: US CA La Jolla US CT New Haven US MA Boston
- Agency: Jones Day
- Main IPC: C07K14/705
- IPC: C07K14/705
Abstract:
The invention provides isolated N-methyl-D-aspartate type 3B (NR3B) polypeptides, functional fragments and peptides, encoding nucleic acid molecules and polynucleotides, and specific antibodies. Also provided are excitatory glycine receptors, containing either NR3B or NR3A polypeptides. Further provided are methods for detecting excitatory glycine receptor ligands, agonists and antagonists. The invention also provides related diagnostic and therapeutic methods.
Public/Granted literature
- US20110045098A1 EXCITATORY GLYCINE RECEPTORS AND METHODS Public/Granted day:2011-02-24
Information query
