A high-power light-emitting diode (LED) driving circuit relates to a photoelectric technology field. An anode of D1 is connected to a constant current direct current (DC) power supply, and a cathode of D1 is connected to LED1, LED4, and one end of R1 and R2. LED1, ED2, and LED3 are connected in serial and then are connected to a collector of Q1, and LED4, LED5, and LED6 are connected in serial and then are connected to a collector of Q2. Emitters of the Q1 and Q2 are grounded. DZ1 is connected to LED1, LED2, and LED3 in parallel, and DZ2 is connected to LED4, LED5, and LED6 in parallel. The other end of R1 is respectively connected to a base of Q1 and one end of C2, and the other end of C2 is connected to the collector of Q2. The other end of R2 is respectively connected to a base of Q2 and one end of C1, and the other end of C1 is connected to the collector of Q1. The driving circuit is capable of completely controlling a temperature of LED chips, avoiding use of a large area of aluminum to dissipate heat, and reducing material cost.