Invention Grant
- Patent Title: Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
- Patent Title (中): 与心血管疾病相关的遗传多态性，检测方法及其应用
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Application No.: US12500378Application Date: 2009-07-09
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Publication No.: US08216786B2Publication Date: 2012-07-10
- Inventor: Dov Shiffman , James J. Devlin , Judy Z. Louie , Eric Boerwinkle
- Applicant: Dov Shiffman , James J. Devlin , Judy Z. Louie , Eric Boerwinkle
- Applicant Address: US CA Alameda
- Assignee: Celera Corporation
- Current Assignee: Celera Corporation
- Current Assignee Address: US CA Alameda
- Agency: Celera Corporation
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/04
Abstract:
The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
Public/Granted literature
- US20100035983A1 GENETIC POLYMORPHISMS ASSOCIATED WITH CARDIOVASCULAR DISEASES, METHODS OF DETECTION AND USES THEREOF Public/Granted day:2010-02-11
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