Invention Grant
- Patent Title: Methods for the inactivation of microorganisms in biological fluids, flow through reactors and methods of controlling the light sum dose to effectively inactivate microorganisms in batch reactors
- Patent Title (中): 生物流体中微生物灭活的方法,流经反应器的方法和控制光总剂量以有效灭活间歇反应器中的微生物的方法
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Application No.: US13100570Application Date: 2011-05-04
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Publication No.: US08377375B2Publication Date: 2013-02-19
- Inventor: Heinz Anderle , Peter Matthiessen , Hans-Peter Schwarz , Peter Turecek , Thomas Kreil , Daniel R. Boggs
- Applicant: Heinz Anderle , Peter Matthiessen , Hans-Peter Schwarz , Peter Turecek , Thomas Kreil , Daniel R. Boggs
- Applicant Address: US IL Deerfield CH Glattpark (Opfikon)
- Assignee: Baxter International Inc.,Baxter Healthcare S.A.
- Current Assignee: Baxter International Inc.,Baxter Healthcare S.A.
- Current Assignee Address: US IL Deerfield CH Glattpark (Opfikon)
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: A61L2/00
- IPC: A61L2/00 ; G01N31/16 ; G01N23/00 ; G01N11/00 ; A61N5/00

Abstract:
The present invention relates to a method for determining an effective dose of monochromatic or polychromatic light from one or more light sources to inactivate microorganisms present in a biological fluid, preferably a non-transparent fluid. Moreover, there is provided a method for the inactivation of microorganism in a biological fluid in a flow-through-reactor. Moreover, the invention advantageously provides a flow-through-reactor with one or more thermostated light sources. The invention further provides a method of controlling the light sum dose of monochromatic or polychromatic light emitted from one or more light sources to effectively inactivate microorganisms present in a biological fluid in a batch reactor.
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