Invention Grant
- Patent Title: Controlled release micro-capsule for osteogenic action
- Patent Title (中): 用于成骨作用的控释微胶囊
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Application No.: US13203603Application Date: 2010-02-26
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Publication No.: US08496964B2Publication Date: 2013-07-30
- Inventor: Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
- Applicant: Prabhat Ranjan Mishra , Ritu Trivedi , Girish Kumar Gupta , Avinash Kumar , Varsha Gupta , Srikanta Kumar Rath , Kamini Srivastava , Naibedya Chattopadhyay , Anil Kumar Dwivedi
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Abelman, Frayne & Schwab
- Priority: IN384/DEL/2009 20090227
- International Application: PCT/IN2010/000115 WO 20100226
- International Announcement: WO2010/097814 WO 20100902
- Main IPC: A61K9/52
- IPC: A61K9/52 ; A61K9/50 ; A61K31/70 ; B01J13/00 ; B05D3/00 ; A01N43/04
Abstract:
The present invention relates to a microcapsule for controlled release of flavanoid compound and a process for preparation thereof. The microcapsule comprising a core particle consisting of a calcium salt, Pluronic F68 [poly (ethylene oxide-co-polypropylene oxide), block poly oxyethylene-polypropylene block copolymer], loaded with a flavanoid compound, the resulting core particle having a plurality of alternate layers of cationic and anionic polyelectrolytes adsorbed thereon and an outer layer formed by a bile salt, wherein the flavanoid is ranging between 10 to 96% by weight.
Public/Granted literature
- US20110305754A1 CONTROLLED RELEASE MICRO-CAPSULE FOR OSTEOGENIC ACTION Public/Granted day:2011-12-15
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