Invention Grant
- Patent Title: Laser illumination systems and methods for dual-excitation wavelength non-linear optical microscopy and micro-spectroscopy systems
- Patent Title (中): 用于双激发波长非线性光学显微镜和微光谱系统的激光照明系统和方法
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Application No.: US13351831Application Date: 2012-01-17
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Publication No.: US08792156B1Publication Date: 2014-07-29
- Inventor: Khanh Kieu , Nasser Peyghambarian , Xiaoliang Sunney Xie , Christian W. Freudiger , Dan Fu
- Applicant: Khanh Kieu , Nasser Peyghambarian , Xiaoliang Sunney Xie , Christian W. Freudiger , Dan Fu
- Applicant Address: US MA Cambridge US AZ Tucson
- Assignee: President and Fellows of Harvard College,The Arizona Board of Regents on Behalf of the University of Arizona
- Current Assignee: President and Fellows of Harvard College,The Arizona Board of Regents on Behalf of the University of Arizona
- Current Assignee Address: US MA Cambridge US AZ Tucson
- Agency: Gesmer Updegrove LLP
- Main IPC: H01S3/10
- IPC: H01S3/10 ; G01J3/44 ; G02F1/37

Abstract:
An illumination system is disclosed for providing dual-excitation wavelength illumination for non-linear optical microscopy and micro-spectroscopy. The illumination system includes a laser system, an optical splitting means, a frequency shifting system, and a picosecond amplifier system. The laser system includes a laser for providing a first train of pulses at a center optical frequency ω1. The optical splitting means divides the first train of pulses at the center optical frequency ω1 into two trains of pulses. The frequency shifting system shifts the optical frequency of one of the two trains of pulses to provide a frequency shifted train of pulses. The picosecond amplifier system amplifies the frequency shifted train of pulses to provide an amplified frequency-shifted train of pulses having a pulse duration of at least 0.5 picoseconds.
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