Invention Grant
US08802121B2 Silane-functionalized hydrophobic α(1→4)glucopyranose polymers and polymeric matrices for implantation or injection
有权
硅烷官能化疏水性α（1→4）吡喃葡萄糖聚合物和聚合物基质用于植入或注射
- Patent Title: Silane-functionalized hydrophobic α(1→4)glucopyranose polymers and polymeric matrices for implantation or injection
- Patent Title (中): 硅烷官能化疏水性α（1→4）吡喃葡萄糖聚合物和聚合物基质用于植入或注射
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Application No.: US12792365Application Date: 2010-06-02
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Publication No.: US08802121B2Publication Date: 2014-08-12
- Inventor: Aleksey V. Kurdyumov , Nathan A. Lockwood , Joram Slager , Dale G. Swan , Robert Hergenrother
- Applicant: Aleksey V. Kurdyumov , Nathan A. Lockwood , Joram Slager , Dale G. Swan , Robert Hergenrother
- Applicant Address: US MN Eden Prairie
- Assignee: Surmodics, Inc.
- Current Assignee: Surmodics, Inc.
- Current Assignee Address: US MN Eden Prairie
- Agency: Kagan Binder, PLLC
- Main IPC: A61F13/00
- IPC: A61F13/00 ; B32B9/04 ; B32B9/06 ; B32B15/04 ; C08G63/91 ; C08G65/32 ; C08L67/00 ; C08L71/00
Abstract:
Silane-functionalized hydrophobic α(1→4)glucopyranose polymers and polymeric matrices are described. Biodegradable matrices can be formed from hydrophobic α(1→4)glucopyranose polymers with reactive pendent silyl ether groups. Reaction of the silyl ether groups provides improved matrix formation through bonding to a device surface of a device, polymer-polymer crosslinking, or both. Biodegradable matrices can be used for the preparation of implantable and injectable medical devices, including those that release a bioactive agent.
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