Invention Grant
- Patent Title: Quinazolinone-type compounds as CRTH2 antagonists
- Patent Title (中): 喹唑啉酮类化合物作为CRTH2拮抗剂
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Application No.: US13878654Application Date: 2011-10-06
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Publication No.: US08927559B2Publication Date: 2015-01-06
- Inventor: Robert G. Aslanian , Christopher W. Boyce , Robert D. Mazzola, Jr. , Brian A. McKittrick , Kevin D. McCormick , Anandan Palani , Jun Qin , Haiqun Tang , Dong Xiao , Younong Yu , John P. Caldwell , Elizabeth Helen Kelley , Hongjun Zhang , Phieng Siliphaivanh , Rachel N. MacCoss , Joey L. Methot , Jolicia Polivina Gauuan , Qin Jiang , Andrew J. Leyhane , Purakkattle Johny Biju , Li Dong , Xianhai Huang , Ning Shao , Wei Zhou , Pawan K. Dhondi , Ashwin U. Rao
- Applicant: Robert G. Aslanian , Christopher W. Boyce , Robert D. Mazzola, Jr. , Brian A. McKittrick , Kevin D. McCormick , Anandan Palani , Jun Qin , Haiqun Tang , Dong Xiao , Younong Yu , John P. Caldwell , Elizabeth Helen Kelley , Hongjun Zhang , Phieng Siliphaivanh , Rachel N. MacCoss , Joey L. Methot , Jolicia Polivina Gauuan , Qin Jiang , Andrew J. Leyhane , Purakkattle Johny Biju , Li Dong , Xianhai Huang , Ning Shao , Wei Zhou , Pawan K. Dhondi , Ashwin U. Rao
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Eric A. Meade; Catherine D. Fitch
- International Application: PCT/US2011/055054 WO 20111006
- International Announcement: WO2012/051036 WO 20120419
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/517 ; C07D239/72 ; C07D401/00

Abstract:
This application provides for compounds of the formula Formula I or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associated with the CRTH2 receptor.
Public/Granted literature
- US20130210805A1 QUINAZOLINONE-TYPE COMPOUNDS AS CRTH2 ANTAGONISTS Public/Granted day:2013-08-15
Information query
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