Invention Grant
- Patent Title: Method for preventing the crystallisation of pharmaceuticals in a polymer film
- Patent Title (中): 防止聚合物膜中药物结晶的方法
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Application No.: US13504970Application Date: 2010-10-26
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Publication No.: US08932665B2Publication Date: 2015-01-13
- Inventor: Johannes Josef Leonhard , Walter Mueller
- Applicant: Johannes Josef Leonhard , Walter Mueller
- Applicant Address: DE Andernach
- Assignee: LTS Lohmann Therapie-Systeme AG
- Current Assignee: LTS Lohmann Therapie-Systeme AG
- Current Assignee Address: DE Andernach
- Agency: ProPat, L.L.C.
- Priority: DE102009052972 20091112
- International Application: PCT/EP2010/006535 WO 20101026
- International Announcement: WO2011/057714 WO 20110519
- Main IPC: A61F13/00
- IPC: A61F13/00 ; A61F13/02 ; A61K9/70 ; B05D3/02 ; A61K31/381 ; A61K9/00

Abstract:
The invention relates to a method for preventing the crystallization of a pharmaceutical in a polymer film, wherein the solvent-containing coating compound, which comprises a matrix-forming polymer or polymer mixture and at least one pharmaceutical and is spread to produce the polymer film, is temporarily dried at temperatures that is at least 10° C. above the melting temperature of the pharmaceutical contained in the coating compound. The maximum temperature is thus higher than that which is required for mere drying and obviates the need for an additional, time-consuming and expensive work step.
Public/Granted literature
- US20120213912A1 METHOD FOR PREVENTING THE CRYSTALLISATION OF PHARMACEUTICALS IN A POLYMER FILM Public/Granted day:2012-08-23
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