An intelligent serial interface circuit in accordance with one embodiment of the invention can include a first communication interface circuit for enabling a first communication protocol. The intelligent serial interface circuit can also include a second communication interface circuit for enabling a second communication protocol. Furthermore, the intelligent serial interface circuit can include a detector circuit coupled to the first communication interface circuit and the second communication interface circuit. The detector circuit can be for automatically detecting a factor that indicates automatically enabling the first communication interface circuit and automatically disabling the second communication interface circuit. The detector circuit can be for detecting a coupling of a pin of the first communication interface circuit that is not used by the second communication interface circuit.