Invention Grant
- Patent Title: Method for producing a drug delivery system on the basis of polyelectrolyte complexes
- Patent Title (中): 基于聚电解质复合物制备药物递送系统的方法
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Application No.: US13638413Application Date: 2011-03-30
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Publication No.: US09078805B2Publication Date: 2015-07-14
- Inventor: Martin Mueller
- Applicant: Martin Mueller
- Applicant Address: DE Dresden
- Assignee: LEIBNIZ-INSTITUT FUER POLYMER-FORSCHUNG DRESDEN E.V.
- Current Assignee: LEIBNIZ-INSTITUT FUER POLYMER-FORSCHUNG DRESDEN E.V.
- Current Assignee Address: DE Dresden
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: DE102010003615 20100401
- International Application: PCT/EP2011/054905 WO 20110330
- International Announcement: WO2011/121019 WO 20111006
- Main IPC: B05D3/04
- IPC: B05D3/04 ; A61F2/00 ; A61J3/00 ; A61L31/16 ; A61K9/00 ; A61K9/51 ; A61L17/00 ; A61L27/34 ; A61L27/54

Abstract:
A method that relates to the fields of polymer chemistry, pharmacy and medicine and releases drugs as a component of implants into the environment of the implant. A method that, in a simple and easily reproducible manner, generates a drug delivery system, which releases drugs in a locally targeted and controllably delayed manner. Polyanions and polycations are mixed in a liquid in a non-stoichiometric ratio, relative to the charged monomer units, wherein drugs are added to the polyelectrolytes either before, during or after the mixing, or charge-carrying drugs and an oppositely charged polyelectrolyte are mixed, and after the mixing the polyelectrolyte complex produced is applied to the surface of a medical structure or material or is positioned on the surface directly at the location where the drug is to be released.
Public/Granted literature
- US20130108774A1 METHOD FOR PRODUCING A DRUG DELIVERY SYSTEM ON THE BASIS OF POLYELECTROLYTE COMPLEXES Public/Granted day:2013-05-02
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