Invention Grant
US09078805B2 Method for producing a drug delivery system on the basis of polyelectrolyte complexes 有权
基于聚电解质复合物制备药物递送系统的方法

Method for producing a drug delivery system on the basis of polyelectrolyte complexes
Abstract:
A method that relates to the fields of polymer chemistry, pharmacy and medicine and releases drugs as a component of implants into the environment of the implant. A method that, in a simple and easily reproducible manner, generates a drug delivery system, which releases drugs in a locally targeted and controllably delayed manner. Polyanions and polycations are mixed in a liquid in a non-stoichiometric ratio, relative to the charged monomer units, wherein drugs are added to the polyelectrolytes either before, during or after the mixing, or charge-carrying drugs and an oppositely charged polyelectrolyte are mixed, and after the mixing the polyelectrolyte complex produced is applied to the surface of a medical structure or material or is positioned on the surface directly at the location where the drug is to be released.
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