A monocentric lens-based multi-scale imaging system is disclosed. Embodiments of the present invention comprise a monocentric lens as an objective lens that collects light from a scene. Monocentric lenses in accordance with the present invention include a spherical central lens element and a plurality of lens shell sections that collectively reduce at least one of spherical and chromatic aberration from the magnitude introduced by the spherical lens element itself. A plurality of secondary lenses image the scene through the objective lens and further reduce the magnitude of aberrations introduced by the objective lens. A plurality of sensor arrays converts optical sub-images of the scene into a plurality of digital images, which can then be used to form a composite image of the scene.