Invention Grant
US09260461B2 Water-soluble derivatives and prodrugs of acacetin and methods of making and using thereof
有权
acacetin的水溶性衍生物和前药及其制备和使用方法
- Patent Title: Water-soluble derivatives and prodrugs of acacetin and methods of making and using thereof
- Patent Title (中): acacetin的水溶性衍生物和前药及其制备和使用方法
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Application No.: US14171228Application Date: 2014-02-03
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Publication No.: US09260461B2Publication Date: 2016-02-16
- Inventor: Gui-Rong Li , Feng Lin
- Applicant: Versitech Limited , Shanghai Institute of Pharmaceutical Industry
- Applicant Address: HK Hong Kong
- Assignee: Versitech Limited
- Current Assignee: Versitech Limited
- Current Assignee Address: HK Hong Kong
- Agency: Pabst Patent Group LLP
- Main IPC: A61K31/35
- IPC: A61K31/35 ; C07D311/00 ; C07F9/655

Abstract:
Water-soluble derivatives and/or prodrugs of acacetin are described herein. The compounds can be used as cardioprotection agents against myocardial infarction induced by ischemia-reperfusion. In one embodiment the compounds are used to treat ischemic cardiac diseases. In the preferred embodiment, the compounds are used to treat and/or prevent myocardial infarction in humans.
Public/Granted literature
- US20150218193A1 Water-Soluble Derivatives and Prodrugs of Acacetin and Methods of Making and Using Thereof Public/Granted day:2015-08-06
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