公开(公告)号：US20250069516A1

公开(公告)日：2025-02-27

申请号：US18813083

申请日：2024-08-23

Applicant: Versitech Limited

Inventor： Wai Tung Wilton FOK ,  Kui Kai Gary LAU ,  Yingxian CHEN ,  Hau Lam Elton YEUNG ,  Wun Yin LAM

IPC: G09B5/06 ,  A61B5/00 ,  A61B5/11

Abstract: A system for providing personalized community-based post-stroke rehabilitation is disclosed. The system includes a user-end module, a cloud platform module, and a therapist-end module. The user-end module is configured to provide schedule information with instructions of at least one specific exercise and to show at least one image or video, in which the user-end module provides a camera view page to record a target image or video and to record a target user's performance metric. The cloud platform module is configured to receive and store the target user's performance metric from the user-end module. The therapist-end module is permitted to log in the cloud platform module and receive the target user's performance metric from the cloud platform module, and the therapist-end module is further configured to visualize the target user's performance metric so as to show exercise waveform comprising quantitative data for qualitative analysis.

公开(公告)号：US20250043403A1

公开(公告)日：2025-02-06

申请号：US18708980

申请日：2021-11-12

Applicant: VERSITECH LIMITED

Inventor： Mingxin Huang ,  Litao Liu ,  Lit Man Poon ,  Wing Hong Chin

IPC: C22C38/52 ,  C22C38/00 ,  C22C38/02 ,  C22C38/06 ,  C22C38/20 ,  C22C38/44 ,  C22C38/46 ,  C22C38/48 ,  C22C38/50 ,  C22C38/58

Abstract: The present invention provides an antibacterial and antiviral copper-containing stainless steel, and a preparation method for and the use of a stainless-steel conforming to the composition thereof. The copper-containing stainless steel comprises a stainless steel matrix and a copper-rich phase evenly distributed in the stainless steel matrix, wherein the copper content of the copper-containing stainless steel is 6-30 wt %. The preparation method therefor comprises the manufacturing of a small stainless steel product mainly using powder metallurgy technology, and the manufacturing of a large stainless steel sheet, bar or pipe mainly using a composite process without significant thermal deformation. Compared with a traditional antibacterial stainless steel, the composition design of the present invention contains sufficient copper-rich precipitated phases, such that the antibacterial and antiviral copper-containing stainless steel of the present invention can achieve both a good killing effect on bacteria and a virus killing capacity comparable with that of pure copper, can be used for preparing the integral body or the whole of parts such as cutters, elevator buttons, railings, handrails, door handles and cups, and can effectively kill bacteria and viruses existing on the surfaces thereof.

公开(公告)号：US20250017952A1

公开(公告)日：2025-01-16

申请号：US18717355

申请日：2022-10-19

Applicant: SASTRA DEEMED UNIVERSITY ,  VERSITECH LIMITED

Inventor： Prasanna NEELAKANTAN ,  Adline Princy SOLOMON ,  Karthi SHANMUGAM

IPC: A61K31/7076 ,  A61P31/10

Abstract: The present invention relates to a compound for treating fungal disease, wherein said compound provide target-specific inhibition of fungal adhesion, biofilm formation, and filamentation without affecting their growth, at very low concentration. The compound of the present invention is selected from FDA approved drugs Cangrelor. Further, the present invention provides a composition comprising compound of the present invention and a pharmaceutically acceptable carrier. Further, the present invention provides a method of treating fungal infections using the compound and/or composition of the present invention. Furthermore, uses of the compound and/or composition is also being provided in the present disclosure.

公开(公告)号：US12163979B2

公开(公告)日：2024-12-10

申请号：US17975030

申请日：2022-10-27

Applicant: VERSITECH LIMITED ,  City University of Hong Kong

Inventor： Ning Xi ,  Song Wang ,  Pengtao Liu ,  Zhiyong Sun ,  Lixin Dong ,  Chaojian Hou ,  Donglei Chen ,  Wenqi Zhang

IPC: G01Q30/02 ,  C12Q1/6869 ,  C23C14/16 ,  C23C14/30 ,  C23C14/34 ,  C23C14/58 ,  C23C16/04 ,  C23C16/40 ,  C23C16/56 ,  G01Q20/02 ,  G01Q30/20 ,  G01Q60/38 ,  G01Q70/16 ,  G03F7/00 ,  G16B40/20

Abstract: A nano scale robotic system for single cell DNA sequencing of a strand of DNA positioned on a slide utilizes an atomic force microscope (AFM) having an end effector in the form of a cantilever with a tip. The AFM causes its cantilever tip to scan over the base pairs of the DNA strand. A pair of spaced-apart electrodes at the tip makes contact with opposite sides of the DNA strand and the current between bases of the DNA strand is measured by a current measurement system connected to the electrodes. An artificial intelligence-based data analytic system determines the DNA sequence based on the current from the current measuring system. The AFM tip is guided over the DNA strand by comparing compressed desired intensity local scan images and compressed actual intensity local scan images and using the difference to control the location of the tip.

公开(公告)号：US20240331144A1

公开(公告)日：2024-10-03

申请号：US18580989

申请日：2022-07-18

Applicant: Versitech Limited ,  The Education University of Hong Kong

Inventor： Man Fung YUEN ,  Gilbert Chiu Sing LUI ,  Jianliang LU ,  Keith Wan Hang CHIU ,  Wai Kay Walter SETO ,  Philip Leung Ho YU

IPC: G06T7/00 ,  G06T11/00

CPC classification number: G06T7/0012 ,  G06T11/006 ,  G06T2207/10081 ,  G06T2207/20081 ,  G06T2207/30056 ,  G06T2207/30096 ,  G06T2207/30168

Abstract: A novel medical image generation approach synthesizes thin-cut computerized tomography (CT) images from thick-cut CT ones as inputs. First thick-cut CT images are obtained by maximizing the pixel-wise intensity of five or more than five continuous thin-cut ones after image registration. Second, the obtained thick-cut CT images are fed into a generator block which adopts an encoder-decoder architecture, where each thick-cut image is encoded into low-dimensional embedding space before decoding into multiple thin-cut ones. Third, a discriminator focuses on distinguishing original real thin-cut images from synthetic thin-cut images. An adversarial mechanism between the generator and discriminator causes the discriminator's output to provide an effective gradient update of the network parameters for the generator to increasingly improve the generator's ability to synthesize higher-quality thin-cut images and in turn promotes the discriminator's discriminating capability.

公开(公告)号：US20240307427A1

公开(公告)日：2024-09-19

申请号：US18594986

申请日：2024-03-04

Applicant: VERSITECH LIMITED ,  Advanced Biomedical Instrumentation Centre Limited

Inventor： Shing Fung Chow ,  Kam Hung Low ,  Si Nga Wong

IPC: A61K31/706 ,  A61K9/00 ,  A61K31/60

CPC classification number: A61K31/706 ,  A61K9/0075 ,  A61K31/60

Abstract: Provided is a cocrystals of remdesivir (RDV) composed of a 1:1 molar ratio of RDV and benzoic acid derivative. The benzoic acid derivative can be salicylic acid (SA). The RDV-SA cocrystal are formed by either liquid-assisted grinding or spray-drying, followed by thermal annealing to facilitate cocrystal formation. The RDV-SA cocrystals can be formulated as inhalable dry powders and included in a medicament for use in treatments for influenza viral infections, such as COVID-19. The inhalable RDV-SA cocrystal dry powders is suitable for deep lung delivery, with good dissolution performance.

公开(公告)号：US20240276867A1

公开(公告)日：2024-08-15

申请号：US18563314

申请日：2022-05-31

Applicant: Versitech Limited ,  Hong Kong Quantum AI Lab Limited

Inventor： Chi-Ming Che ,  Kar-Wai Lo ,  Gang Cheng

IPC: H10K85/30 ,  C07F15/00 ,  C09K11/06 ,  H10K50/12 ,  H10K101/10

CPC classification number: H10K85/346 ,  C07F15/0086 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1014 ,  C09K2211/1044 ,  C09K2211/1059 ,  C09K2211/185 ,  H10K50/12 ,  H10K2101/10

Abstract: Described herein are dinuclear platinum(II) emitter complexes and their methods of making and using thereof. The design of the dinuclear platinum(II) emitters results in short radiative lifetimes and high quantum yields. The dinuclear platinum(II) emitter complexes can be used to fabricate blue emitting OLEDs.

公开(公告)号：US11852754B2

公开(公告)日：2023-12-26

申请号：US16767009

申请日：2018-12-05

Applicant: VERSITECH LIMITED

Inventor： Yang Zhang ,  Yuexin Guo ,  Wei-Ning Lee

IPC: A61B8/14 ,  G01S7/52 ,  G01S15/89

CPC classification number: G01S7/52026 ,  A61B8/14 ,  G01S15/8927 ,  G01S15/8959

Abstract: System and method of ultrasound imaging methodology are provided. The system and method can include directing an array to transmit sets of cascaded titled ultrasound waves towards a tissue sample, decoding reflected signals through summing, subtracting, and delay operations. The reflected signals can be reconstructed to provide a final decoded output.

公开(公告)号：US20230391625A1

公开(公告)日：2023-12-07

申请号：US18033080

申请日：2021-10-21

Applicant: VERSITECH LIMITED

Inventor： Zhiqin Chu ,  Tongtong Zhang

IPC: C01B32/28

CPC classification number: C01B32/28 ,  C01P2004/64 ,  C01P2006/80

Abstract: Disclosed are methods of purifying nanodiamonds and a method of making essentially pure nanodiamonds each involving mixing nanodiamonds with at least one salt to form a mixture; heating the mixture at a temperature from 200° C. to 1,000° C. for a time from 10 minutes to 10 hours; and combining a liquid with the heated mixture and centrifuging at a speed of 30 rcf to 25,000 rcf for a time from 10 seconds to 60 minutes to provide purified nanodiamonds. With the methods of the invention, pure NDs can be produced by one-step processing after air oxidation, without the need for any further centrifugation acts. Furthermore, the developed salt-assisted air oxidation method enables facile scale-up manufacturing of clean NDs, with a rounded shape transformed from original shard-like shape, which is impossible to achieve using any existing purification method.

公开(公告)号：US20230279442A1

公开(公告)日：2023-09-07

申请号：US18066129

申请日：2022-12-14

Applicant: Versitech Limited ,  Centre for Oncology and Immunology Limited

Inventor： Siu Lun Wong ,  Tsz Lo Yuen

IPC: C12N15/90 ,  C12N9/22 ,  C12N15/11

CPC classification number: C12N15/907 ,  C12N9/22 ,  C12N15/11 ,  C12N2310/20 ,  C12N2800/80

Abstract: Disclosed are SaCas9 protein variants, constructs encoding such variants, compositions comprising such variants and constructs, and methods of using the variants, constructs, and compositions. In some forms, the disclosed variants comprise the mutation Y239H and do not comprise the mutation R245A. Also disclosed are constructs encoding any of the disclosed variants for expression of the variant in a host of interest. Also disclosed are methods of editing a sequence of interest.