Invention Grant
US09279102B2 Temperature-responsive substrate for cell culture and production method thereof
有权
用于细胞培养的温度敏感性底物及其制备方法
- Patent Title: Temperature-responsive substrate for cell culture and production method thereof
- Patent Title (中): 用于细胞培养的温度敏感性底物及其制备方法
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Application No.: US13819685Application Date: 2011-08-31
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Publication No.: US09279102B2Publication Date: 2016-03-08
- Inventor: Masamichi Nakayama , Teruo Okano
- Applicant: Masamichi Nakayama , Teruo Okano
- Applicant Address: JP Tokyo
- Assignee: TOKYO WOMEN'S MEDICAL UNIVERSITY
- Current Assignee: TOKYO WOMEN'S MEDICAL UNIVERSITY
- Current Assignee Address: JP Tokyo
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: JP2010-208506 20100831
- International Application: PCT/JP2011/069839 WO 20110831
- International Announcement: WO2012/029882 WO 20120308
- Main IPC: B05D1/00
- IPC: B05D1/00 ; C12N5/00 ; C08F293/00
Abstract:
To form a temperature-responsive surface for cell culture by simple processes, said temperature-responsive surface for cell culture being capable of efficiently culturing cells. Cultured cells or a cell sheet can be efficiently removed from the temperature-responsive surface for cell culture by merely changing the temperature of the substrate surface. To coat the substrate surface with a block copolymer, in which a water insoluble polymer segment is coupled with a temperature-responsive polymer segment, in an amount of 0.8 to 3.0 μg/cm2 of the temperature-responsive polymer.
Public/Granted literature
- US20140212973A1 TEMPERATURE-RESPONSIVE SUBSTRATE FOR CELL CULTURE AND PRODUCTION METHOD THEREOF Public/Granted day:2014-07-31
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