Invention Grant
US09334544B2 Cellulase compositions having improved thermostability and synergy
有权
具有改善的热稳定性和协同作用的纤维素酶组合物
- Patent Title: Cellulase compositions having improved thermostability and synergy
- Patent Title (中): 具有改善的热稳定性和协同作用的纤维素酶组合物
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Application No.: US14516390Application Date: 2014-10-16
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Publication No.: US09334544B2Publication Date: 2016-05-10
- Inventor: Devin L. Trudeau , Frances H. Arnold , Toni M. Lee , Stephen L. Mayo
- Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Applicant Address: US CA Pasadena
- Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Current Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
- Current Assignee Address: US CA Pasadena
- Agency: Lewis Roca Rothgerber Christie LLP
- Main IPC: C12N9/26
- IPC: C12N9/26 ; C12P19/14 ; C12P19/02 ; C12N9/42

Abstract:
A variant Cel5a endoglucanase has increased thermostability, increased enzymatic activity and/or increased expression in a host, relative to wild type Cel5a. The improved variant Cel5a endoglucanase may be used to hydrolyze more cellulose at a higher temperature for a more efficient and cost-effective production of biofuels as compared to wild type Cel5a. A variant Cel5a endoglucanase is combined with variant Cel6a and variant Cel7a cellobiohydrolases resulting in more effective hydrolysis of cellulose.
Public/Granted literature
- US20150050701A1 CELLULASE COMPOSITIONS HAVING IMPROVED THERMOSTABILITY AND SYNERGY Public/Granted day:2015-02-19
Information query
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