Invention Grant
- Patent Title: Assessing the risk of a major adverse cardiac event in patients with chest pain
- Patent Title (中): 评估胸痛患者主要不良心脏事件的风险
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Application No.: US13707725Application Date: 2012-12-07
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Publication No.: US09365888B2Publication Date: 2016-06-14
- Inventor: Stanley L. Hazen , Renliang Zhang
- Applicant: Stanley L. Hazen , Renliang Zhang
- Applicant Address: US OH Cleveland
- Assignee: The Cleveland Clinic Foundation
- Current Assignee: The Cleveland Clinic Foundation
- Current Assignee Address: US OH Cleveland
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: C12Q1/28
- IPC: C12Q1/28 ; G01N33/68

Abstract:
Methods for characterizing the near term risk of experiencing a major adverse cardiac event in a patient presenting to an Emergency Department with chest pain are provided. In one embodiment the method comprises determining the level of myeloperoxidase (MPO) activity and/or mass in a bodily sample obtained from the patient. Levels of MPO activity or MPO mass in bodily samples from the test subject are then compared to a control value in comparable bodily samples obtained from a control population. Such comparison can also be used to determine the near term treatment of the patient.
Public/Granted literature
- US20130102019A1 ASSESSING THE RISK OF A MAJOR ADVERSE CARDIAC EVENT IN PATIENTS WITH CHEST PAIN Public/Granted day:2013-04-25
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