Invention Grant
- Patent Title: Polyphenol proteasome inhibitors, synthesis, and methods of use
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Application No.: US14057956Application Date: 2013-10-18
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Publication No.: US09399631B2Publication Date: 2016-07-26
- Inventor: Q. Ping Dou , Tak-Hang Chan , David M. Smith
- Applicant: UNIVERSITY OF SOUTH FLORIDA , MCGILL UNIVERSITY , THE HONG KONG POLYTECHNIC UNIVERSITY
- Applicant Address: US FL Tampa CA Montreal HK Hung Hom
- Assignee: UNIVERSITY OF SOUTH FLORIDA,MCGILL UNIVERSITY,THE HONG KONG POLYTECHNIC UNIVERSITY
- Current Assignee: UNIVERSITY OF SOUTH FLORIDA,MCGILL UNIVERSITY,THE HONG KONG POLYTECHNIC UNIVERSITY
- Current Assignee Address: US FL Tampa CA Montreal HK Hung Hom
- Agency: Saliwanchik Lloyd & Eisenschenk
- Main IPC: C07C59/68
- IPC: C07C59/68 ; C07D311/60 ; C07C69/88 ; C07C235/54
Abstract:
The present invention relates to synthetic green tea derived polyphenolic compounds, their modes of syntheses, and their use in inhibiting proteasomal activity and in treating cancers. The present invention is also directed to pharmaceutical compositions useful in methods of inhibiting proteasomes and of treating cancers.
Public/Granted literature
- US20140045931A1 POLYPHENOL PROTEASOME INHIBITORS, SYNTHESIS, AND METHODS OF USE Public/Granted day:2014-02-13
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