Invention Grant
- Patent Title: Method for the automated production consisting of a molecular layer of amphiphilic molecules and a device for producing said molecular layer
- Patent Title (中): 由两亲分子的分子层组成的自动生产方法和用于制备所述分子层的装置
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Application No.: US13979129Application Date: 2012-01-10
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Publication No.: US09403184B2Publication Date: 2016-08-02
- Inventor: Jan Behrends , Gerhard Baaken
- Applicant: Jan Behrends , Gerhard Baaken
- Applicant Address: DE Freiburg
- Assignee: Albert-Ludwigs-Universität Freiburg
- Current Assignee: Albert-Ludwigs-Universität Freiburg
- Current Assignee Address: DE Freiburg
- Agency: Arnold & Porter LLP
- Agent Todd A. Lorenz
- Priority: DE102011008205 20110110
- International Application: PCT/EP2012/000081 WO 20120110
- International Announcement: WO2012/095299 WO 20120719
- Main IPC: B05D1/40
- IPC: B05D1/40 ; G01N33/50 ; B81C1/00 ; B05C11/08 ; B05C11/02

Abstract:
The invention is related to a method and an apparatus for the automated fabrication of a molecular layer made from amphiphilic molecules, in particular lipids for a lipid bilayer membrane, in the apparatus, which has a support substrate for supporting the molecular layer, a rotation element, which can be rotated on top of the support substrate, and an actuator device, by means of which the rotation element can be automatically rotated, wherein the rotation element has an outer surface, which is formed hydrophobic at least in sections, the method having the following steps: placing a first solvent, which contains amphiphilic molecules, in a region above the support substrate; causing the automatic rotation of the rotation element above the support substrate; moving the first solvent between the support substrate and the rotation element by the interaction of the rotating rotation element with the first solvent, thus forming the molecular layer.
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