Invention Grant
- Patent Title: Uses of hypoxia-inducible factor inhibitors
- Patent Title (中): 缺氧诱导因子抑制剂的使用
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Application No.: US13513659Application Date: 2010-06-25
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Publication No.: US09427413B2Publication Date: 2016-08-30
- Inventor: Yang Liu , Yin Wang , Yan Liu , Sami N. Malek , Pan Zheng
- Applicant: Yang Liu , Yin Wang , Yan Liu , Sami N. Malek , Pan Zheng
- Applicant Address: US MD Rockville
- Assignee: OncoImmune, Inc.
- Current Assignee: OncoImmune, Inc.
- Current Assignee Address: US MD Rockville
- Agency: Polsinelli PC
- Agent Ron Galant
- International Application: PCT/US2010/039910 WO 20100625
- International Announcement: WO2011/068563 WO 20110609
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A61K31/33 ; A61K31/00 ; A61K31/395 ; A61K31/498 ; A61K31/565 ; A61K45/06
Abstract:
The present invention relates to treating a hematologic cancer using a Hypoxia-Inducible Factor (HIF inhibitor). The invention also relates to inducing acute myeloid leukemia remission using the HIF inhibitor. The invention further relates to inhibiting a maintenance or survival function of a cancer stem cell (CSC) using the HIF inhibitor.
Public/Granted literature
- US20120264697A1 USES OF HYPOXIA-INDUCIBLE FACTOR INHIBITORS Public/Granted day:2012-10-18
Information query
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