Invention Grant
- Patent Title: Mass spectrometry for multiplexed quantitation using multiple frequency notches
- Patent Title (中): 使用多个频率切口进行多重定量的质谱
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Application No.: US13901137Application Date: 2013-05-23
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Publication No.: US09437407B2Publication Date: 2016-09-06
- Inventor: Graeme Conrad McAlister , Wilhelm Haas , Steven P. Gygi
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: H01J49/00
- IPC: H01J49/00 ; G01N33/50
Abstract:
A method of performing a mass spectrometry analysis includes labeling each of a plurality of samples with a corresponding chemical tag; forming a first plurality of ions from molecules in the samples; selecting a subset of the first plurality of ions, the subset being selected by isolating ions of the first plurality of ions in a plurality of ranges of mass-to-charge; forming a second plurality of ions by fragmenting ions in the subset; and measuring information indicative of a quantity of each of the plurality of chemical tags present in each of the plurality of samples.
Public/Granted literature
- US20130334414A1 MASS SPECTROMETRY FOR MULTIPLEXED QUANTITATION USING MULTIPLE FREQUENCY NOTCHES Public/Granted day:2013-12-19
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