Some demonstrative embodiments include apparatuses, devices, systems and methods of communicating a wakeup packet. For example, an apparatus may include circuitry configured to cause a first wireless device to modulate a preamble of a wakeup packet according to an Orthogonal Frequency Division Multiplexing (OFDM) scheme; modulate a payload of the wakeup packet according to an On-Off keying (OOK) modulation scheme over a plurality of OFDM tones; and transmit the wakeup packet to a second wireless device.