Invention Grant
- Patent Title: Systems and methods for improved robustness for quadrupole mass spectrometry
- Patent Title (中): 改善四极杆质谱稳定性的系统和方法
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Application No.: US14690307Application Date: 2015-04-17
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Publication No.: US09496126B2Publication Date: 2016-11-15
- Inventor: Johnathan Wayne Smith
- Applicant: Thermo Finnigan LLC
- Applicant Address: US CA San Jose
- Assignee: Thermo Finnigan LLC
- Current Assignee: Thermo Finnigan LLC
- Current Assignee Address: US CA San Jose
- Agent David A. Schell
- Main IPC: H01J49/32
- IPC: H01J49/32 ; H01J47/06 ; G01N30/00 ; H01J49/42 ; H01J49/00

Abstract:
A method for analyzing a sample by mass spectrometry includes producing ions from the sample, delivering the ions to an entrance of a multipole, and applying oscillatory and resolving DC voltages to electrodes of the multipole. The oscillatory and resolving DC voltages cause the multipole to selectively transmit to its distal end ions within a range of mass-to-charge ratios (m/z's) determined by the amplitudes of the oscillatory and resolving DC voltages. The method further includes acquiring data representative of the spatial distributions of ions transmitted by the multipole at a plurality of consecutive time points, and deconvolving the acquired data to produce a mass spectrum. Deconvolving the acquired data includes processing the data to compress a dynamic range of intensity values in the data.
Public/Granted literature
- US20160307745A1 Systems and Methods for Improved Robustness for Quadrupole Mass Spectrometry Public/Granted day:2016-10-20
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