A power gating circuit and a control method for power gating switch thereof are provided. The power gating circuit includes a first switch, the power gating switch, a pre-charge circuit, and a control circuit. A first terminal and a second terminal of the first switch are coupled to a first voltage and the control terminal of the power gating switch, respectively. A first terminal and a second terminal of the power gating switch are coupled to a second voltage and a function circuit, respectively. An input signal defines a powered period of the function circuit. According to the input signal, the pre-charge circuit pre-charges the control terminal of the power gating switch during the first sub-period of the powered period, and the control circuit controls the first switch to charge the control terminal of the power gating switch by the first voltage during the second sub-period of the powered period.