Invention Grant
- Patent Title: Aggregation induced emission of fluorescent bioprobes and methods of using the same
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Application No.: US13899070Application Date: 2013-05-21
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Publication No.: US09618453B2Publication Date: 2017-04-11
- Inventor: Benzhong Tang , Ka Ming Ng , Qian Luo , Yong Yu , Yuning Hong , Jianzhao Liu , Sijie Chen , Wing Yip Lam , Zhengke Wang , Wei Qin , Tsz Kin Kwok
- Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Applicant Address: CN Kowloon, Hong Kong
- Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: CN Kowloon, Hong Kong
- Agency: Nath, Goldberg & Meyer
- Agent Joshua B. Goldberg
- Main IPC: C12Q1/04
- IPC: C12Q1/04 ; G01N21/64 ; B82Y15/00 ; G01N1/30 ; C07F7/08
Abstract:
Provided herein are fluorescent bioprobes comprising fluorogens that exhibit aggregation-induced emission (AIE) labeled on biomolecules. The present subject matter relates to a fluorescent bioprobe comprising one or more fluorogen labeled on chitosan. The present subject matter is also directed to methods of preparing the fluorescent bioprobes, methods of labeling and detecting DNA and/or proteins with the fluorescent bioprobe, and methods of cell imaging including live cell tracking.
Public/Granted literature
- US20130266953A1 AGGREGATION INDUCED EMISSION OF FLUORESCENT BIOPROBES AND METHODS OF USING THE SAME Public/Granted day:2013-10-10
Information query
